Fig. 3. Photo-induced changes in the membrane capacity of PC12 cells containing TC1. (a-d) Representative illumination-induced whole-cell currents (x: control), and effects of treatment with 100 µM DIDS (a: y, b: DIDS) and with 10 µM SKF96365 (c: y, d: SKF96365). (e) The time courses of the membrane capacitance in whole cell patch-clamp under illumination (black bar, hν: 525−550 nm, input power 2 mW cm−2) are shown for PC12 cells treated in the presence of TC1-loaded cpHDL (TC1) and the absence of TC1 (control). (b) The average of the photo-induced changes in the membrane capacitance in the presence (TC1) and absence (control) of TC1. *p<0.05 vs. control (n = 5).